Community Empowerment Through Health Education on Rational Antibiotic Use in Sempu, Banyuwangi

Winartiana; Anis Akhwan Dhafin; Maharani Dwi P; Elsa Mahardika P; Tantik Tandela

doi:10.30994/jceh.v9i2.841

Authors

Winartiana Department of Pharmacy, Faculty of Health Sciences, Universitas Kadiri, Kediri, Indonesia
Anis Akhwan Dhafin Department of Pharmacy, Faculty of Health Sciences, Universitas Kadiri, Kediri, Indonesia
Maharani Dwi P Department of Pharmacy, Faculty of Health Sciences, Universitas Kadiri, Kediri, Indonesia
Elsa Mahardika P Department of Pharmacy, Faculty of Health Sciences, Universitas Kadiri, Kediri, Indonesia
Tantik Tandela Department of Pharmacy, Faculty of Health Sciences, Universitas Kadiri, Kediri, Indonesia

DOI:

https://doi.org/10.30994/jceh.v9i2.841

Keywords:

Antibiotics, Health Education, Community Service, Antibiotic Resistance, Self-Medication

Abstract

Unsupervised antibiotic use remains a public health concern and may contribute to antimicrobial resistance, inappropriate medication use, and antibiotic-related renal impairment. Limited knowledge regarding antibiotic indications, acquisition, dosage, and resistance highlights the need for targeted community education. This community service activity aimed to improve residents’ knowledge, perceptions, and behavioral intentions regarding rational antibiotic use in RT 02, RW 04, Sempu, Banyuwangi Regency. The activity was conducted in May 2026 using a participatory educational approach with a one-group pretest-posttest design. A total of 35 respondents were selected through purposive sampling. Knowledge was assessed using a 21-item questionnaire covering antibiotic indications, acquisition, dosage, storage, resistance, and renal impairment risks. The mean knowledge score increased from 44.6 ± 12.8 to 92.9 ± 6.4, with a mean difference of 48.3 ± 13.1 points (p < 0.001). The proportion of respondents categorized as having good knowledge increased from 5.7% to 91.4%. The greatest improvements were observed in knowledge of appropriate antibiotic indications (57.1%) and antibiotic resistance (51.4%). Positive changes in perceptions and behavioral intentions were also observed, with 88.6% of respondents reporting that they would no longer purchase antibiotics without a prescription and 91.4% expressing interest in continued mentoring. Participatory health education improved knowledge and supported positive behavioral intentions toward rational antibiotic use. Collaboration with pharmacists, primary healthcare professionals, health cadres, and local pharmaceutical service facilities is recommended to strengthen continuous education, monitoring, and adherence to prescription requirements.

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References

Bellino, A., Lofrano, G., Carotenuto, M., Libralato, G., & Baldantoni, D. (2018). Antibiotic effects on seed germination and root development of tomato (Solanum lycopersicum L.). Ecotoxicology and Environmental Safety, 148, 135–141. https://doi.org/https://doi.org/10.1016/j.ecoenv.2017.10.006

Bhardwaj, K., Shenoy M, S., Baliga, S., Unnikrishnan, B., & Baliga, B. S. (2021). Knowledge, attitude, and practices related to antibiotic use and resistance among the general public of coastal south Karnataka, India – A cross-sectional survey. Clinical Epidemiology and Global Health, 11, 100717. https://doi.org/https://doi.org/10.1016/j.cegh.2021.100717

Chautrakarn, S., Khumros, W., & Phutrakool, P. (2021). Self-Medication With Over-the-counter Medicines Among the Working Age Population in Metropolitan Areas of Thailand. Frontiers in Pharmacology, Volume 12. https://doi.org/10.3389/fphar.2021.726643

Christanti JV, Setiadi AP, Setiawan E, Presley B, Halim SV, Wardhani SA, Sunderland B, Wibowo YI.( 2024).Community-Based Approach to Promote Rational Use of Antibiotics in Indonesia: The Development and Assessment of an Education Program for Cadres. Community Health Equity Res Policy. Apr;44(3):281-293. doi: 10.1177/2752535X231184029. Epub 2023 Jul 2. PMID: 37393556.

da Costa, B. C., Giroldo, A. C., de Oliveira, L. B., Prado, C. E. do, Caetano, I. G. de A., de Moraes, D. S. C., Boll, K. M., Donega, S. L. Z., Scacco, G., Domingues, G. G. C., Quintino, G. K. L., Martins, C. B., & Evangelista, O. A. (2026). PHARMACEUTICAL INTERVENTIONS IN ANTIBIOTIC THERAPY IN ADULT INTENSIVE CARE UNITS OF A UNIVERSITY HOSPITAL. The Brazilian Journal of Infectious Diseases, 30, 104688. https://doi.org/https://doi.org/10.1016/j.bjid.2026.104688

Dewi, L., Hendrayanti, H., & Nurhayati, C. (2020). Pemeriksaan Bahan Kimia Obat (Bko) Natrium Diklofenak Dalam Beberapa Sediaan Jamu Rematik Yang Beredar Di Pasar Purwadadi Subang. Jurnal Sabdariffarma: Jurnal Ilmiah Farmasi, 8(1), 5-10.

Dobrek, L. (2023). A Synopsis of Current Theories on Drug-Induced Nephrotoxicity. Life (Basel, Switzerland), 13(2). https://doi.org/10.3390/life13020325

Dwi Putri Rejeki, Verawati, Siti Fara Syiva Al Inaya, Ida Mukhlisa, & Rosa Mardiana. (2025). Edukasi Rasionalitas Penggunaan Antibiotik: Upaya Pencegahan Resistensi Melalui Peningkatan Pengetahuan Dan Sikap Ibu Di Desa Pulo Pisang, Sigli. Jurnal Mitra Pengabdian Farmasi, 4(3 SE-Articles), 1–5. https://ejurnal.akfar-mandiri.ac.id/index.php/abdimas/article/view/60

Elkhadry, S. W., & Tahoon, M. A. H. (2024). Health literacy and its association with antibiotic use and knowledge of antibiotic among Egyptian population: cross sectional study. BMC Public Health, 24(1), 2508. https://doi.org/10.1186/s12889-024-19668-3

Ghasemian, A., Sargeran, K., Khami, M. R., & Shamshiri, A. R. (2024). Effects of educational interventions based on the theory of planned behavior on oral cancer-related knowledge and tobacco smoking in adults: a cluster randomized controlled trial. BMC Cancer, 24(1), 45. https://doi.org/10.1186/s12885-024-11845-2

Hamao, N., Ito, I., Konishi, S., Tanabe, N., Oi, I., Yasutomo, Y., Kadowaki, S., & Hirai, T. (2025). Incidence of and risk factors for side effects associated with antibiotic treatment for pneumonia. Journal of Infection and Chemotherapy, 31(9), 102789. https://doi.org/https://doi.org/10.1016/j.jiac.2025.102789

Karuniawati H, Hassali MAA, Suryawati S, Ismail WI, Taufik T, Hossain MS. Assessment of Knowledge, Attitude, and Practice of Antibiotic Use among the Population of Boyolali, Indonesia: A Cross-Sectional Study. Int J Environ Res Public Health. 2021 Aug 4;18(16):8258.

Katzung, B. G., & Vanderah, T. W. (2021). Farmacologia básica e clínica. Artmed Editora.

Kumar, S., Agrawal, S., Sinha, S., & Yasmeen, T. (2024). Primary Caregiver Knowledge about Self-Medication of Antibiotics in Children Aged 0-12 Years. Chonnam Medical Journal, 60(3), 174–179. https://doi.org/10.4068/cmj.2024.60.3.174

Liao, Z., Su, X., Luo, T., Zhao, X., Guo, Y., Xu, X., Wang, F., Luo, G., & Zhan, R. (2025). A side-effect-free chemotactic-antibacterial wound dressing for programmatic trapping, killing of bacteria, and wound repair. Materials Today Bio, 35, 102594. https://doi.org/https://doi.org/10.1016/j.mtbio.2025.102594

Nguyen, N. V., Marothi, Y., & Sharma, M. (2022). Knowledge, Attitude, and Practice Regarding Antibiotic Use and Resistance for Upper Respiratory Tract Infections among the Population Attending a Mass Gathering in Central India: A Cross-Sectional Study. Antibiotics, 11(11), 1473.

Risnawati, R. (2021). Implikatur pada wacana vaksinasi covid-19 di akun instagram @kemenkes_ri. KEMBARA: Jurnal Keilmuan Bahasa, Sastra, Dan Pengajarannya, 7(2 SE-Articles), 529–547. https://doi.org/10.22219/kembara.v7i2.17193

Romanova, A., Rubinelli, S., & Diviani, N. (2024). Improving health and scientific literacy in disadvantaged groups: A scoping review of interventions. Patient Education and Counseling, 122, 108168.

Singh H, Samkange-Zeeb F, Kolschen J, Herrmann R, Hübner W, Barnils NP, Brand T, Zeeb H, Schüz B. (2024). Interventions to promote health literacy among working-age populations experiencing socioeconomic disadvantage: systematic review. Front Public Health.Feb 19;12:1332720. doi: 10.3389/fpubh.2024.1332720

Shehadeh, M. B., Suaifan, G. A. R. Y., & Hammad, E. A. (2016). Active educational intervention as a tool to improve safe and appropriate use of antibiotics. Saudi Pharmaceutical Journal, 24(5), 611–615. https://doi.org/https://doi.org/10.1016/j.jsps.2015.03.025

Storms, H., Claes, N., Aertgeerts, B., & Van den Broucke, S. (2017). Measuring health literacy among low literate people: an exploratory feasibility study with the HLS-EU questionnaire. BMC Public Health, 17(1), 475. https://doi.org/10.1186/s12889-017-4391-8

Tanha, N., Areskog Lejbman, I., De Bus, L., De Pascale, G., Garnacho-Montero, J., Leone, M., Fujitan, S., De Waele, J. J., Torisson, G., & Sjövall, F. (2024). Clinical outcomes in combination versus mono antibiotic therapy in ICU admitted patients with a suspected infection - A substudy of the DIANA study. Journal of Critical Care, 80, 154501. https://doi.org/https://doi.org/10.1016/j.jcrc.2023.154501

Tarhan, M. S., & Guc, O. (2026). Association between health literacy and antibiotic-related knowledge, attitudes, and behaviors. BMC Public Health, 26(1), 656. https://doi.org/10.1186/s12889-026-26416-2

Unsleber, S., Wohlleben, W., & Stegmann, E. (2019). Diversity of peptidoglycan structure—Modifications and their physiological role in resistance in antibiotic producers. International Journal of Medical Microbiology, 309(6), 151332. https://doi.org/https://doi.org/10.1016/j.ijmm.2019.151332

Yunita SL, Yang HW, Chen YC, Kao LT, Lu YZ, Wen YL, To SY, Huang YL. (2022). Knowledge and practices related to antibiotic use among women in Malang, Indonesia. Front Pharmacol. Oct 24;13:1019303. doi: 10.3389/fphar.2022.1019303. PMID: 36353493; PMCID: PMC9637850.

Yusef, D., Babaa, A. I., Bashaireh, A. Z., Al-Bawayeh, H. H., Al-Rijjal, K., Nedal, M., & Kailani, S. (2018). Knowledge, practices & attitude toward antibiotics use and bacterial resistance in Jordan: A cross-sectional study. Infection, Disease & Health, 23(1), 33–40. https://doi.org/https://doi.org/10.1016/j.idh.2017.11.001

Zanichelli, V., Sharland, M., Cappello, B., Moja, L., Getahun, H., Pessoa-Silva, C., Sati, H., van Weezenbeek, C., Balkhy, H., Simão, M., Gandra, S., & Huttner, B. (2023). The WHO AWaRe (Access, Watch, Reserve) antibiotic book and prevention of antimicrobial resistance. In Bulletin of the World Health Organization (Vol. 101, Number 4, pp. 290–296). https://doi.org/10.2471/BLT.22.288614